Fig. 2

Gene enrichment analysis for DMGs shows differential immune signatures between tumor and normal PBMCs. Immune-related terms significantly enriched in the Gene Ontology (blue box), the MGI Mammalian Phenotype (pink box), the KEGG pathway (yellow box), and the Human Gene Atlas (purple box) are shown. The color of dots means which group is hypermethylated (‘N-hyper’ is expressed as blue, ‘T-hyper’ as purple, ‘B-hyper’ as orange, and ‘C-hyper’ as red. The size of the dots indicates the statistical importance (according to -log10 adjusted p-value). The table corresponding to this figure shows the genes included in each term, which is in Table S7