Fig. 2
From: Robustness of single-cell RNA-seq for identifying differentially expressed genes
Transcriptome profiles from bulk and pseudo-bulk RNA-seq are modestly correlated. A Number of genes detected by bulk and pseudo-bulk, and the overlaps. B Venn diagram for examples of panel A. C log2(TPM + 1) of genes detected in both bulk and pseudo-bulk data. D Correlations between bulk and pseudo-bulk data. Abundance of genes not detected in one of the two datasets was set to 0 TPM. E An example of the correlation. Genes were divided into quartiles based on the abundance in bulk RNA-seq. EC, iPSC-derived endothelial cells; VSMC, iPSC-derived vascular smooth muscle cells; TPM, transcripts per million