Fig. 3

Significant differential microsporidia mRNA, lncRNA and miRNA heatmap analysis between 5-day embryos, 1-day larvae, 5-day larvae, and 10-day larvae challenged by N. bombycis congenital infection. A: Significant differential microsporidia mRNA heatmap analysis was showed at four different stages, and the DE genes were fallen into 5 clusters with the highest expressed gene clusters; B: Significant differential microsporidia lncRNA heatmap analysis was showed at four different stages; C: Significant differential microsporidia miRNA heatmap analysis was showed at four different stages, and the DE miRNAs were fallen into 4 clusters. Genes which are down-regulated are depicted in blue, with darker colors representative of greater down-regulation. Up-regulated genes are depicted in red, with darker shading corresponding to a greater degree of expression. T1: 5-day embryos with N. bombycis congenital infection; T2: 1-day larvae with N. bombycis congenital infection; T3: 1-day larvae with N. bombycis congenital infection; T4: 10-day larvae with N. bombycis congenital infection