Table 2 List of predicted virulence-associated genes in E. faecium RAOG174, compared to the E. faecium DO genome
VF class | Virulence factors | Related genes | E. faecium RAOG174 (Prediction) | E. faecium strain DO |
|---|---|---|---|---|
Adherence | Acm | acm |  +  | HMPREF0351_12281 |
Ebp pili | ebpA |  +  | HMPREF0351_11394 | |
ebpB |  +  | HMPREF0351_11393 | ||
ebpC |  +  | HMPREF0351_11392 | ||
srtC |  +  | HMPREF0351_11391 | ||
EcbA | ecbA |  +  | HMPREF0351_11828 | |
EfaA | efaA |  +  | HMPREF0351_10500 | |
Esp | esp |  +  | - | |
Scm | scm |  +  | HMPREF0351_12673 | |
SgrA | sgrA |  +  | HMPREF0351_11523 | |
Streptococcal lipoprotein rotamase A (Streptococcus) | slrA |  +  | - | |
Anti-phagocytosis | Capsule | cpsA/uppS |  +  | HMPREF0351_11682 |
cpsB/cdsA |  +  | HMPREF0351_11681 | ||
Biofilm formation | BopD | bopD |  +  | HMPREF0351_10415 |
Enzyme | Hyaluronidase | Undetermined |  +  | - |
Serine-threonine phosphatase (Listeria) | stp |  +  | - | |
Immune evasion | Capsule (Staphylococcus) | capL |  +  | - |
Capsule (Streptococcus) |  |  +  | - | |
rgpG |  +  | - | ||
Iron uptake | Periplasmic binding protein-dependent ABC transport systems (Vibrio) | vctC |  +  | - |
Protease | Serine protease (Streptococcus) | htrA/degP |  +  | - |
Surface protein anchoring | Lipoprotein diacylglyceryl transferase (Listeria) | lgt |  +  | - |