Fig. 1

The process of data collection and database construction. Upper part shows the process of the data collection, including manually curating literature and integrating public databases. The left panel describes our manual extraction of experimental microbe-disease information. The right panel gives the list of public databases of information source. Lower part shows the types of associations, basic information of each association entry and GMMAD functions. The left panel shows the three types of associations. Disease-metabolite is the core association, and it is provided exclusively by our database. The middle panel tells the basic information of each entry, including details of disease description, microbial category, molecular mass of metabolite and so on. The right panel provides a list of GMMAD’s main functions