Fig. 3

Differences of gene expression during regeneration in Platynereis dumerilii A) Heatmaps showing differentially expressed genes (DEGs) between each pair of conditions, with up-regulated genes on the left (shades of red) and down-regulated genes on the right (shades of blue). Each line represents the control (or reference) conditions, each column represents the test conditions. For example, 3395 transcripts are up-regulated at 5 dpa compared to 0 dpa (as indicated by the arrow). The color key corresponds to the number of transcripts in each box. A transcript was considered as up-regulated (or down-regulated) with an FDR < 0.05 and a logFC > 1 (resp. < 1). DEGs were identified using edgeR [58]. B Volcano plots for sequential comparisons (0 dpa vs 1 dpa, 1 dpa vs 2 dpa, 2 dpa vs 3 dpa, 3 dpa vs 5 dpa, 5 dpa vs NA). Each dot represents a transcript, with colors indicating different values for FDR and logFC. In grey: FDR > 0.05; -1 < logFC < 1. In green: FDR > 0.05; logFC < -1 or logFC > 1. In blue: FDR < 0.05; -1 < logFC < 1. And finally, in red: FDR <0.05, -1 < logFC < 1. Thus, the DEGs are depicted in red