Fig. 5
From: Predictive value of CCL2 in the prognosis and immunotherapy response of glioblastoma multiforme
Correlation between immune cell infiltration and CCL2 in GBM. A Immune cell score of CD4+ T cells in CCL2-high and CCL2-low GBM tissue was calculated with the TIMER2.0 algorithm. B The correlation between CCL2 expression and immune score of CD4+ T cells was analyzed with Spearman’s correlation analysis. C-H Similar analyses for macrophages (C, D), neutrophils (E, F), and myeloid dendritic cells (G, H) were performed and results were displayed as in A and B. I, J The heatmap of immune cell score in CCL2-high and CCL2-low GBM tissue (I) and the percentage abundance of tumor infiltrating immune cells in each sample (J) were depicted. The statistical difference was calculated through the Wilcox test. ** p < 0.01, *** p < 0.001