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Fig. 3 | BMC Genomics

Fig. 3

From: Single-cell characterization of self-renewing primary trophoblast organoids as modeling of EVT differentiation and interactions with decidual natural killer cells

Fig. 3

Single-cell characterization of trophoblast organoids (TO). (A) Cell clusters for TO sample and EVT-TO sample from 10× Genomics scRNA-seq analysis visualized by UMAP. Colors indicate cell type or state. p, proliferative; CCC, cytotrophoblast cell column. (B) Feature plots showing the expression of canonical marker genes for the defined cell types. (C) Dot plots showing the expression of known lineage-specific genes for different EVT subtypes. (D) GO analysis of the DEGs for the three different subtypes of EVTs. (E) Proportion of TO system in each scRNA-seq-defined cluster in the undifferentiation TO state and differentiation EVT-TO state

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