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Fig. 6 | BMC Genomics

Fig. 6

From: Single-cell characterization of self-renewing primary trophoblast organoids as modeling of EVT differentiation and interactions with decidual natural killer cells

Fig. 6

Single-cell characterization of dNKs-EVT-TO co-cultures. (A) Cell clusters for dNKs-EVT-TO sample from 10× Genomics scRNA-seq analysis visualized by UMAP. Colors indicate cell type or state. (B) Feature plots showing the expression of canonical marker genes for the defined cell types. (C) GO analysis enriched different terms on the DEGs for the three different subtypes of EVTs. (D) GO analysis enriched shared terms in EVT2 and EVT3. (E) Pseudotime ordering of the trophoblast clusters indicate the dNKs pathways in dNKs-EVT-TO co-cultures. (F) Annotations query of the trophoblast clusters in the dNKs-EVT-TO co-cultures by Seurat mapping analysis. Reference database: the in vivo single-cell dataset of placenta (E-MTAB-6701)

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BMC Genomics

ISSN: 1471-2164

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