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Fig. 4 | BMC Genomics

Fig. 4

From: Comprehensive exploration of the involvement of cuproptosis in tumorigenesis and progression of neuroblastoma

Fig. 4

Development and validation of cuproptosis scores for neuroblastoma (NB). (A) alluvial diagram of 2 cuproptosis subtypes (high and low score), cuproptosis score values, 3 gene clusters, and clinical results; (B) differences in cuproptosis score values of the high and low-score subtypes as well as the gene clusters A, B, and C; (C) Kaplan–Meier analysis of the overall survival (OS) between the 2 cuproptosis score groups; (D) clinical features of the 2 cuproptosis score groups; (E, F) the (E) uniCox and (F) multiCox analyses demonstrating the independent prognostic value of the cuproptosis score and multiple clinical factors; (G) a nomogram for estimating the one, three, and five-year OS of individuals with NB in the TARGET-NB cohort; and (H) calibration curves for verifying the developed nomogram

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