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Fig. 9 | BMC Genomics

Fig. 9

From: Comprehensive exploration of the involvement of cuproptosis in tumorigenesis and progression of neuroblastoma

Fig. 9

PDHA1 promotes proliferation, invasiveness, and lymphatic metastasis of neuroblastoma (NB) cells in vitro via cell cycle pathway (A) western blot analysis of NB cell lines after transfection with si-PDHA1#2 and si-PDHA1#1 to decrease the expression level of PDHA1; (B) cell colony formation efficiency of the knockdown of PDHA1 NB cells as well as control cells; (C) invasiveness of PDHA1 knockdown NB cells and control cells; (D) lymphoangiogenetic efficiency of HLECs incubated with the culture medium from PDHA1 knockdown NB cells and control cells; (E, F) distributions of PDHA1 knockdown NB cells and control cells by cell cycle through flow cytometry. (p < 0.05 *; p < 0.01 **; p < 0.001 ***)

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