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Fig. 4 | BMC Genomics

Fig. 4

From: IL-33 priming and antigenic stimulation synergistically promote the transcription of proinflammatory cytokine and chemokine genes in human skin mast cells

Fig. 4

Genes synergically upregulated by IL-33 priming and IgE receptor cross-linking are enriched in genes encoding pro-inflammatory cytokines and chemokines. A Gene ontology (GO) enrichment analysis of the upregulated genes in clusters four and six. P-values were calculated by a one-side Fisher’s exact test with the adjustment of Benjamini–Hochberg method. B Heatmap representation of top ranked genes in each gene family in clusters four and six. The numbers indicate RNA reads (FPKM). log2FC: log2[EIgECL+IL-33/(EIgECL + EIL-33)]. Data represents the average reads generated from two biological samples

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