Table 2 Median number of variants depends on the used reference genome and region of origin. Numbers indicate the decrease (-) or increase (+) in median number of variants per 10,000 bp when Illumina WGS reads are mapped to PvPAM in comparison to PvP01 or PvW1. For example, South American reads show 5.26 core genome SNPs less per 10,000 bp when mapped to the PvPAM genome in comparison to the PvP01 genome. Values are shown separately for the core genome and subtelomeric genome, and variants are divided into SNPs and indels (insertions and deletions). * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001 (paired Wilcoxon signed-rank test). African samples originate from Eritrea (5), Ethiopia (5), Sudan (5) and Uganda (3), South Asian samples from Afghanistan (5), India (5) and Pakistan (5), and Southeast Asian samples from Cambodia (5), Malaysia (5), Myanmar (5), Papua New Guinea (5), Thailand (5) and Vietnam (5). N = number of Illumina WGS samples

From: A new Plasmodium vivax reference genome for South American isolates