Fig. 3
Reconstructed metabolic pathways for Rhodotorula sphaerocarpa ETNP2018. The outer bi-layered membrane represents plasma membrane surrounding the cytosol, the inner bi-layered membrane the mitochondrion, and the inner single-layered membrane the peroxisome; shapes embedded into membranes represent transport proteins. Arrow and transport protein color gradients represent requirement for a specific cofactor in reaction or transport, with the second color of the gradient indicating preferred direction: Black/White, no cofactor required; Light Blue/White, H2O; Purple/Pink, ATP; Purple/Blue, ADP; Yellow/White, NAD+; Teal/Yellow, NADH; Green/Yellow, NADP+; Green/White, NADPH; Red/Pink, FAD2+; Black/Red, O2; Purple/Red, H2O2. Abbreviations are as follows: EtOH, Ethanol; CoA, Coenzyme A; THF, tetrahydrofolate; Pi, Inorganic Phosphate; AICAR, 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside; PRPP, phosphoribosyl diphosphate; AMP, adenosine monophosphate; ATP, adenosine triphosphate; UDP, uridine diphosphate; UTP, uridine triphosphate; UDPG, UDP-α -D-Glucose; sFA, Saturated Fatty Acid; FAD, Flavin Adenine Dinucleotide; FMN, Flavin Mononucleotide; CoQ6, Ubiquinone-6; CoQ6H2, Ubiquinol-6; CoQ10, Ubiquinone-10; Cyt. C, Cytochrome C