Fig. 2
From: ATACAmp: a tool for detecting ecDNA/HSRs from bulk and single-cell ATAC-seq data
ATAC-seq features of ecDNA/HSR and performance of ATACAmp. (A) ATAC-seq profile of ecDNA regions in the COLO320DM and COLO320HSR cell line. (The upper two tracks are ecDNA-forming regions in the COLO320DM cell line and the lower two tracks are HSR-forming regions in the COLO320HSR cell line) (B) The links of the highest scoring co-amplified regions in the COLO320DM cell line. (C) The performances of different ecDNA calling softwares. (D) Comparison of total length of ecDNA detected by different software. (E) Heatmap of Sequencing Depths for False-Positive and Validated AA Regions