Fig. 1

Systematic analysis of epigenetic-related genes. A Volcano maps for 2906 differentially expressed genes (DEGs) based on Gene Expression Omnibus (GEO) database. B Heatmap of DEGs between colorectal cancer (CRC) and normal tissues. C A total of 2906 DEGs were identified from GSE87211 dataset. After overlapping DEGs with 720 epigenetic-related genes (ERGs) and we obtained 56 differentially expressed ERGs (DEERGs). D 56 DEERGs were identified from GSE87211, including 36 upregulated genes and 20 downregulated genes. E The locations of the 56 DEERGs on chromosomes