Table 1 Type I error rates of MRBSS, mvLMM, and 2HiGWAS when \(\Sigma\) is of autoregressive structure
q | \(\rho\) | \(q_0\) | MRBSS | mvLMM | 2HiGWAS |
|---|---|---|---|---|---|
100 | 0.2 | 5% | 0.0698 | 0.0421 | 0.2172 |
10% | 0.0709 | 0.0333 | 0.3176 | ||
20% | 0.0716 | 0.075 | 0.3481 | ||
0.5 | 5% | 0.0701 | 0.0207 | 0.2146 | |
10% | 0.0710 | 0.0378 | 0.3137 | ||
20% | 0.0718 | 0.0391 | 0.3468 | ||
0.9 | 5% | 0.0714 | 0.0506 | 0.1989 | |
10% | 0.0705 | 0.0504 | 0.2963 | ||
20% | 0.0720 | 0.0483 | 0.3379 | ||
200 | 0.2 | 5% | 0.0654 | 0.0204 | 0.1811 |
10% | 0.0656 | 0.047 | 0.1762 | ||
20% | 0.0642 | 0.0497 | 0.1589 | ||
0.5 | 5% | 0.0652 | 0.0442 | 0.1793 | |
10% | 0.0659 | 0.0562 | 0.1741 | ||
20% | 0.0639 | 0.0503 | 0.1554 | ||
0.9 | 5% | 0.0658 | 0.0497 | 0.1657 | |
10% | 0.0656 | 0.0685 | 0.1648 | ||
20% | 0.0645 | 0.0475 | 0.1398 | ||
500 | 0.2 | 5% | 0.0623 | 0.0483 | 0.0717 |
10% | 0.0613 | 0.0653 | 0.0693 | ||
20% | 0.0617 | 0.055 | 0.0699 | ||
0.5 | 5% | 0.0625 | 0.0538 | 0.0705 | |
10% | 0.0617 | 0.0212 | 0.0679 | ||
20% | 0.0617 | 0.0478 | 0.0687 | ||
0.9 | 5% | 0.0625 | 0.0284 | 0.0653 | |
10% | 0.0621 | 0.0501 | 0.0610 | ||
20% | 0.0615 | 0.0490 | 0.0612 |