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Table 1 Summary of genome-wide significant and suggestive SNPs associated with footrot resistance/susceptibility in Portuguese Merino and crossbred animals

From: Genome-wide association study identifies genetic variants underlying footrot in Portuguese Merino sheep

Chr

Position (bp)

A1

A2

p-value

Genomic Region

Functional effect

Gene

Genome-wide significant SNPs

 24

16,664,127

G

T

1.23E-07

UTR3

-

SMG1

 24

16,683,234

G

A

1.69E-07

exon

synonymous

SMG1

 24

16,688,212

T

C

6.16E-07

exon

synonymous

SMG1

Genome-wide suggestive SNPs

 2

260,442,170

C

T

2.93E-06

exon

synonymous

HSPG2

 9

100,456,022

T

G

4.49E-06

intron

-

RALYL

 8

13,714,405

G

A

9.38E-06

UTR5

-

CENPW

 4

42,346,212

T

G

2.08E-05

intron

-

PCLO

 7

3,506,174

C

G

2.06E-05

Intergenic

-

LOC106991156 (dist = 553,763); THBS1 (dist = 161,183)

 15

57,714,827

G

A

3.66E-5

intron

-

KLHL35

  1. Chr chromosome, A1 allele 1, A2 allele 2