Table 4 MSTN rs11333758 association analysis for athletes stratified by performance and compared with controls

Model

Controls n (%)

All high-elite n (%)

OR

95% CI lower

95% CI upper

p-value adjusted

Codominant

 AA

211 (57.8)

25 (49)

1

0.016968

 A/–

137 (37.5)

17 (33.3)

1.05

0.55

2.01

 –/–

17 (4.7)

9 (17.6)

4.47

1.8

11.08

Dominant

 AA

211 (57.8)

25 (49)

1

0.474748

 A/– - –/–

154 (42.2)

26 (51)

1.42

0.79

2.56

Recessive

 AA - A/–

348 (95.3)

42 (82.4)

1

0.004066

 –/–

17 (4.7)

9 (17.6)

4.39

1.84

10.46

Overdominant

 AA - –/–

228 (62.5)

34 (66.7)

1

1

 A/–

137 (37.5)

17 (33.3)

0.83

0.45

1.55

Model

Controls n (%)

All elite n (%)

OR

95% CI lower

95% CI upper

p-value adjusted

Codominant

 AA

211 (57.8)

86 (57.3)

1

1

 A/–

137 (37.5)

60 (40)

1.07

0.72

1.59

 –/–

17 (4.7)

4 (2.7)

0.58

0.19

1.77

Dominant

 AA

211 (57.8)

86 (57.3)

1

1

 A/– - –/–

154 (42.2)

64 (42.7)

1.02

0.69

1.5

Recessive

 AA - A/–

348 (95.3)

146 (97.3)

1

0.56

 –/–

17 (4.7)

4 (2.7)

0.56

0.19

1.7

Overdominant

 AA - –/–

228 (62.5)

90 (60)

1

1

 A/–

137 (37.5)

60 (40)

1.11

0.75

1.64

Model

Controls n (%)

All subelite n (%)

OR

95% CI lower

95% CI upper

p-value adjusted

Codominant

 AA

211 (57.8)

85 (65.9)

1

0.25796

 A/–

137 (37.5)

36 (27.9)

0.65

0.42

1.02

 –/–

17 (4.7)

8 (6.2)

1.17

0.49

2.81

Dominant

 AA

211 (57.8)

85 (65.9)

1

0.21014

 A/– - –/–

154 (42.2)

44 (34.1)

0.71

0.47

1.08

Recessive

 AA - A/–

348 (95.3)

121 (93.8)

1

1

 –/–

17 (4.7)

8 (6.2)

1.35

0.57

3.22

Overdominant

 AA - –/–

228 (62.5)

93 (72.1)

1

0.09222

 A/–

137 (37.5)

36 (27.9)

0.64

0.42

1