Table 5 The results of association analysis for the ACVR2A rs3764955 with athletes stratified by both discipline and performance. Full results are available in Supplementary 1 Table B
From: Genetic variants in myostatin and its receptors promote elite athlete status
Model | Controls n (%) | Sprint/power elite n (%) | OR | 95% CI lower | 95% CI upper | p-value adjusted |
Codominant | ||||||
GG | 158 (43.3) | 22 (52.4) | 1 | 0.07862 | ||
CG | 179 (49) | 13 (31) | 0.52 | 0.25 | 1.07 | |
CC | 28 (7.7) | 7 (16.7) | 1.8 | 0.7 | 4.6 | |
Dominant | ||||||
GG | 158 (43.3) | 22 (52.4) | 1 | 0.52572 | ||
CG - CC | 207 (56.7) | 20 (47.6) | 0.69 | 0.37 | 1.32 | |
Recessive | ||||||
GG - CG | 337 (92.3) | 35 (83.3) | 1 | 0.1464 | ||
CC | 28 (7.7) | 7 (16.7) | 2.41 | 0.98 | 5.91 | |
Overdominant | ||||||
GG - CC | 186 (51) | 29 (69) | 1 | 0.04824 | ||
CG | 179 (49) | 13 (31) | 0.47 | 0.23 | 0.92 | |
Model | Controls n (%) | Mixed-sport sub-elite n (%) | OR | 95% CI lower | 95% CI upper | p-value adjusted |
Codominant | ||||||
GG | 158 (43.3) | 24 (39.3) | 1 | 0.11748 | ||
CG | 179 (49) | 26 (42.6) | 0.96 | 0.53 | 1.73 | |
CC | 28 (7.7) | 11 (18) | 2.59 | 1.14 | 5.87 | |
Dominant | ||||||
GG | 158 (43.3) | 24 (39.3) | 1 | 1.12636 | ||
CG - CC | 207 (56.7) | 37 (60.7) | 1.18 | 0.68 | 2.05 | |
Recessive | ||||||
GG - CG | 337 (92.3) | 50 (82) | 1 | 0.03496 | ||
CC | 28 (7.7) | 11 (18) | 2.65 | 1.24 | 5.65 | |
Overdominant | ||||||
GG - CC | 186 (51) | 35 (57.4) | 1 | 0.70418 | ||
CG | 179 (49) | 26 (42.6) | 0.77 | 0.45 | 1.33 |