Table 3 The results of reverse MR analysis
Outcome Name (id) | No.of SNP | pleiotropy test (p. value) | Cochrane's Q heterogeneity test(Q_pval) | MR method | p.val | OR | or_lci95 | or_uci95 |
|---|---|---|---|---|---|---|---|---|
Genus Prevotella7(id.11182) | 9 | 0.621 | 0.861 | ivw-fe | 0.004 | 0.972 | 0.953 | 0.991 |
MR Egger | 0.232 | 0.955 | 0.890 | 1.023 | ||||
Simple mode | 0.139 | 0.966 | 0.928 | 1.007 | ||||
Weighted mode | 0.101 | 0.964 | 0.928 | 1.002 | ||||
Weighted median | 0.015 | 0.969 | 0.945 | 0.994 | ||||
Genus Anaerofilum(id.2053) | 9 | 0.842 | 0.773 | ivw-fe | 0.017 | 1.020 | 1.004 | 1.037 |
MR Egger | 0.410 | 1.026 | 0.968 | 1.088 | ||||
Simple mode | 0.623 | 1.009 | 0.974 | 1.045 | ||||
Weighted mode | 0.619 | 1.009 | 0.976 | 1.042 | ||||
Weighted median | 0.376 | 1.010 | 0.988 | 1.031 | ||||
Genus Subdoligranulum(id.2070) | 9 | 0.603 | 0.393 | ivw-fe | 0.009 | 1.012 | 1.003 | 1.021 |
MR Egger | 0.264 | 1.021 | 0.988 | 1.055 | ||||
Simple mode | 0.523 | 1.007 | 0.986 | 1.028 | ||||
Weighted mode | 0.562 | 1.006 | 0.987 | 1.026 | ||||
Weighted median | 0.262 | 1.007 | 0.994 | 1.021 | ||||
Family Veillonellaceae(id.2172) | 9 | 0.380 | 0.752 | ivw-fe | 0.010 | 0.988 | 0.979 | 0.997 |
MR Egger | 0.876 | 1.003 | 0.971 | 1.035 | ||||
Simple mode | 0.455 | 0.992 | 0.971 | 1.013 | ||||
Weighted mode | 0.419 | 0.993 | 0.976 | 1.010 | ||||
Weighted median | 0.198 | 0.992 | 0.979 | 1.004 |