Table 4 The detail information of SNPs in reverse MR analysis
Bacterial taxa (outcome) | SNP | Effect allele | Other allele | BETA | SE | P.val | palindromic | F | |||
|---|---|---|---|---|---|---|---|---|---|---|---|
exposure | outcome | exposure | outcome | exposure | outcome | ||||||
genus.Anaerofilum(id.2053) | rs10513202 | G | A | 1.427 | 0.043 | 0.321 | 0.033 | 8.58E-06 | 0.188 | FALSE | 20 |
rs11090513 | T | G | 0.798 | 0.007 | 0.175 | 0.023 | 5.00E-06 | 0.763 | FALSE | 21 | |
rs11230859 | A | G | -0.725 | -0.008 | 0.158 | 0.021 | 4.18E-06 | 0.713 | FALSE | 21 | |
rs12669698 | C | T | 1.127 | 0.030 | 0.255 | 0.032 | 9.73E-06 | 0.342 | FALSE | 20 | |
rs17145573 | A | G | 1.708 | 0.012 | 0.365 | 0.033 | 2.87E-06 | 0.721 | FALSE | 22 | |
rs389558 | T | C | -0.783 | -0.005 | 0.160 | 0.020 | 9.74E-07 | 0.793 | FALSE | 24 | |
rs491806 | C | A | -0.948 | -0.056 | 0.211 | 0.025 | 6.92E-06 | 0.023 | FALSE | 20 | |
rs529324 | A | G | -0.826 | -0.033 | 0.179 | 0.022 | 4.16E-06 | 0.130 | FALSE | 21 | |
rs7778345 | G | A | 0.730 | -0.003 | 0.163 | 0.020 | 7.05E-06 | 0.880 | FALSE | 20 | |
genus.Prevotella7(id.11182) | rs10513202 | G | A | 1.427 | -0.019 | 0.321 | 0.038 | 8.58E-06 | 0.621 | FALSE | 20 |
rs11090513 | T | G | 0.798 | -0.007 | 0.175 | 0.028 | 5.00E-06 | 0.793 | FALSE | 21 | |
rs11230859 | A | G | -0.725 | 0.022 | 0.158 | 0.025 | 4.18E-06 | 0.377 | FALSE | 21 | |
rs12669698 | C | T | 1.127 | -0.039 | 0.255 | 0.038 | 9.73E-06 | 0.297 | FALSE | 20 | |
rs17145573 | A | G | 1.708 | -0.072 | 0.365 | 0.039 | 2.87E-06 | 0.066 | FALSE | 22 | |
rs389558 | T | C | -0.783 | 0.020 | 0.160 | 0.025 | 9.74E-07 | 0.430 | FALSE | 24 | |
rs491806 | C | A | -0.948 | 0.040 | 0.211 | 0.029 | 6.92E-06 | 0.171 | FALSE | 20 | |
rs529324 | A | G | -0.826 | 0.051 | 0.179 | 0.026 | 4.16E-06 | 0.048 | FALSE | 21 | |
rs7778345 | G | A | 0.730 | 0.010 | 0.163 | 0.024 | 7.05E-06 | 0.691 | FALSE | 20 | |
genus.Subdoligranulum(id.2070) | rs10513202 | G | A | 1.427 | 0.004 | 0.321 | 0.017 | 8.58E-06 | 0.809 | FALSE | 20 |
rs11090513 | T | G | 0.798 | 0.008 | 0.175 | 0.013 | 5.00E-06 | 0.502 | FALSE | 21 | |
rs11230859 | A | G | -0.725 | -0.008 | 0.158 | 0.011 | 4.18E-06 | 0.498 | FALSE | 21 | |
rs12669698 | C | T | 1.127 | 0.006 | 0.255 | 0.017 | 9.73E-06 | 0.716 | FALSE | 20 | |
rs17145573 | A | G | 1.708 | 0.048 | 0.365 | 0.017 | 2.87E-06 | 0.005 | FALSE | 22 | |
rs389558 | T | C | -0.783 | 0.002 | 0.160 | 0.011 | 9.74E-07 | 0.876 | FALSE | 24 | |
rs491806 | C | A | -0.948 | 0.004 | 0.211 | 0.013 | 6.92E-06 | 0.741 | FALSE | 20 | |
rs529324 | A | G | -0.826 | -0.007 | 0.179 | 0.012 | 4.16E-06 | 0.549 | FALSE | 21 | |
rs7778345 | G | A | 0.730 | 0.026 | 0.163 | 0.011 | 7.05E-06 | 0.018 | FALSE | 20 | |
family.Veillonellaceae(id.2172) | rs10513202 | G | A | 1.427 | 0.003 | 0.321 | 0.018 | 8.58E-06 | 0.871 | FALSE | 20 |
rs11090513 | T | G | 0.798 | -0.016 | 0.175 | 0.013 | 5.00E-06 | 0.216 | FALSE | 21 | |
rs11230859 | A | G | -0.725 | 0.009 | 0.158 | 0.012 | 4.18E-06 | 0.451 | FALSE | 21 | |
rs12669698 | C | T | 1.127 | -0.033 | 0.255 | 0.017 | 9.73E-06 | 0.055 | FALSE | 20 | |
rs17145573 | A | G | 1.708 | -0.010 | 0.365 | 0.018 | 2.87E-06 | 0.578 | FALSE | 22 | |
rs389558 | T | C | -0.783 | 0.024 | 0.160 | 0.011 | 9.74E-07 | 0.034 | FALSE | 24 | |
rs491806 | C | A | -0.948 | 0.011 | 0.211 | 0.014 | 6.92E-06 | 0.420 | FALSE | 20 | |
rs529324 | A | G | -0.826 | 0.007 | 0.179 | 0.012 | 4.16E-06 | 0.574 | FALSE | 21 | |
rs7778345 | G | A | 0.730 | -0.004 | 0.163 | 0.012 | 7.05E-06 | 0.740 | FALSE | 20 | |