Table 1 List of genes most upregulated in GluIIß knockout A549 cells compared to non-target transfected cells (log 2-fold change value above +8.0)

1

KRT4

ENSG00000170477

14.9181

keratin 4

2

ADH1C

ENSG00000248144

12.5354

alcohol dehydrogenase 1C (class I), gamma polypeptide

3

ANKS4B

ENSG00000175311

12.056

ankyrin repeat and sterile alpha motif domain containing 4B

4

HGF

ENSG00000019991

11.912

hepatocyte growth factor

5

TPTEP1

ENSG00000100181

10.6873

TPTE pseudogene 1

6

AP000547.3

ENSG00000283633

10.5691

novel transcript

7

GJB1

ENSG00000169562

10.2814

gap junction protein beta 1

8

BPIFB1

ENSG00000125999

9.8638

BPI fold containing family B member 1

9

F7

ENSG00000057593

9.68815

coagulation factor VII

10

H19

ENSG00000130600

9.44138

H19, imprinted maternally expressed transcript

11

AC092336.1

ENSG00000249166

9.29137

novel transcript

12

OR51E2

ENSG00000167332

9.12393

olfactory receptor family 51 subfamily E member 2

13

OR51E1

ENSG00000180785

9.00386

olfactory receptor family 51 subfamily E member 1

14

EDN3

ENSG00000124205

8.95679

endothelin 3

15

PRKCB

ENSG00000166501

8.84155

protein kinase C beta

16

PRR15L

ENSG00000167183

8.63558

proline rich 15 like

17

NTS

ENSG00000133636

8.58469

neurotensin

18

SERPINB11

ENSG00000206072

8.55008

serpin family B member 11 (gene/pseudogene)

19

AC008163.1

ENSG00000233491

8.52041

uncharacterized LOC100128317

20

CES5AP1

ENSG00000215478

8.49012

carboxylesterase 5A pseudogene 1

21

CTNND2

ENSG00000169862

8.36217

catenin delta 2

22

LINC02212

ENSG00000249396

8.31637

long intergenic non-protein coding RNA 2212

23

VIL1

ENSG00000127831

8.28829

villin 1

24

LINC01146

ENSG00000258867

8.22176

long intergenic non-protein coding RNA 1146

25

HOXD-AS2

ENSG00000237380

8.06619

HOXD cluster antisense RNA 2

26

NPY6R

ENSG00000226306

8.02453

neuropeptide Y receptor Y6 (pseudogene)