Fig. 4

Construction of co-expression modules for sepsis samples. A Scale-free index analysis and mean connectivity analysis for selecting the best soft power. B Co-expression similarity of all modules based on the hierarchical clustering of module eigengenes. The cut height of 0.3 was chosen to merge similar modules. C The cluster dendrogram and color display of co-expression network modules for all genes. The first color row underneath the dendrogram shows the WGCNA module assignment obtained by the dynamic tree cut method. The bottom color row shows the merged modules based on a correlation threshold of 0.7. D Heatmap of the correlation between module eigengenes and immune cells. The color spectrum represents the correlation coefficient ranging from -1 to 1. *p < 0.05, **p < 0.01