Fig. 2

Breakpoint inference accuracy of the investigated methods on simulated datasets. Two performance metrics are calculated for evaluation: 1) we measure the distance to the nearest predicted breakpoint for each real breakpoint, then sum the distances for all real breakpoints; 2) w is defined as the ratio between the number of inferred breakpoints and the number of real breakpoints. A lower breakpoint distance coupled with w closer to 1 indicate higher inference accuracy. Performance of each method on simulated diploid (Simulation A), triploid (Simulation B) and tetraploid (Simulation C) datasets are evaluated