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Fig. 6 | BMC Genomics

Fig. 6

From: Inferring single-cell copy number profiles through cross-cell segmentation of read counts

Fig. 6

Copy number estimation results of DeepCNA on the 10X Genomics dataset. CHISEL algorithm [16] has clustered the cells into 6 subgroups, and we select one cell from each subpopulation for illustration. Copy number profiles of these cells exhibit significant differences. For instance, cell with barcode “TAAGAGATCAAGAAAC” is a diploid cell that shows few CNAs across the genome; Cells “CTGGTCTGTTGCGGCT” and “GGCCGATGTAACCGAG” show different copy number on chromosome 9q; compared to cell “GGCCGATGTAACCGAG”, cell “TGACTTTGTTTCCATT” has copy number of 3 on chromosome 2, and cell “TGGCTGGGTTACGCGC” shows copy number of 3 on chromosomes 2–3

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