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Fig. 2 | BMC Genomics

Fig. 2

From: Ribosomal profiling of human endogenous retroviruses in healthy tissues

Fig. 2

Profiling of the endoretrotranslatome. a HERV superfamily RPM abundance averages per tissue or cell type. RPM values are calculated based on the total number of filtered reads per sample. b HERV superfamily abundance averages per sample type as a proportion of all HERV-aligned reads. c HERV superfamily RPM abundances per sample in HA_ECs. Dots indicate individual biological replicates with the graphed mean. Error bars indicate ± SEM. (n = 6). d HERV superfamily RPM abundances per sample in HCA_ECs. Dots indicate individual biological replicates with the graphed mean. Error bars indicate ± SEM. (n = 5) e HERV superfamily RPM abundances per sample in ESCs. Dots indicate individual biological replicates with the graphed mean. Error bars indicate ± SEM. (n = 6) f HERV superfamily RPM abundances per sample in brain tissue. Dots indicate individual biological replicates with the graphed mean. Error bars indicate ± SEM. (n = 5) g HERV superfamily RPM abundances per sample in fat tissue. Dots indicate individual biological replicates with the graphed mean. Error bars indicate ± SEM. (n = 6) h HERV superfamily RPM abundances per sample in PHAFs. Dots indicate individual biological replicates with the graphed mean. Error bars indicate ± SEM. (n = 10) i HERV superfamily RPM abundances per sample in hepatocytes. Dots indicate individual biological replicates with the graphed mean. Error bars indicate ± SEM. (n = 5) j HERV superfamily RPM abundances per sample in HUVECs. Dots indicate individual biological replicates with the graphed mean. Error bars indicate ± SEM. (n = 3) k HERV superfamily RPM abundances per sample in VSMCs. Dots indicate individual biological replicates with the graphed mean. Error bars indicate ± SEM. (n = 11) l Heatmap displaying RPM abundances of the top 10 most highly translated HERVs in HA_ECs. (n = 6) m Heatmap displaying RPM abundances of the top 10 most highly translated HERVs in HCA_ECs. (n = 5) n Heatmap displaying RPM abundances of the top 10 most highly translated HERVs in ESCs. (n = 6). o Heatmap displaying RPM abundances of the top 10 most highly translated HERVs in brain tissue. (n = 5). p Heatmap displaying RPM abundances of the top 10 most highly translated HERVs in fat tissue. (n = 6). q Heatmap displaying RPM abundances of the top 10 most highly translated HERVs in PHAFs.(n = 10). r Heatmap displaying RPM abundances of the top 10 most highly translated HERVs in hepatocytes. (n = 5). s Heatmap displaying RPM abundances of the top 10 most highly translated HERVs in HUVECs. (n = 3). t Heatmap displaying RPM abundances of the top 10 most highly translated HERVs in VSMCs. (n = 11)

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