Fig. 3

Visualization of the pooled effect sizes of the sample parameters on quality metrics, acquired from the additive GLMs. NS and (S) label non-significant (P > 0.05) and suggestive (0.003 < P < 0.05) association, whereas the absence of labels indicate significant (P < 0.003) effect. Blue and red colors in the tiles’ background indicate negative and positive pooled effect sizes, respectively. In addition, filled circles within tiles represent homogeneity measures from the meta-analytical models; specifically, their size is proportional to the meta-analytic models' between-reference-genome heterogeneity quantified by I², whereas color represents the heterogeneity variance τ.² (from grey to light green, from small to larger values, respectively)