Identifying patterns to uncover the importance of biological pathways on known drug repurposing scenarios

BMC Genomics

Table 2 Statistical and descriptive analysis of the biological components building both parts of the DREBIOP triples

	Disease 1	Disease 2 Pathway-based treated disease	P-value
Number of genes	105.13	423.66	< 0.05 *
Number of gene-related pathways	391.04	1568.00	< 0.05 *
Number of disease-related pathways	0.00	25.83	< 0.05 ***
Number of drugs	384.6	657.33	< 0.05 *
Number of symptoms	68.60	106.66	< 0.05 *

Data reported in the table correspond to the means obtained for each biological component and part of the triples. The data highlighted in bold refer to the most relevant data in this section since they are the differences in the number of mean pathways between the two sides of the triplet. P-value annotation legend: *: 1.00 × 10⁻² < p < = 5.00 × 10⁻², ***: 1.00 × 10⁻⁴ < p < = 1.00 × 10⁻³

ISSN: 1471-2164