Fig. 4

Performance of M-GBBD and brainMI with different datasets on four representative brain related diseases. A Mean AUC and AUPR values of brainMI with only BFC- and eBFC-based gene networks under 5-CV. B Mean AUC and AUPR values of M-GBBD with BFC-based gene network and sDD/lDD under 5-CV. C Mean AUC and AUPR values of M-GBBD with eBFC-based gene network and sDD/lDD under 5-CV. Statistical significant was estimated using two-tailed Student’s t-test. *, P < 0.05; **, P < 0.01; ***, P < 0.001