Table 2 SNPs associated with RCC in the Korean population at optimal PRS performance (n = 31)

rs67756935

3

33,211,952

C

T

0.0958

2.66E-11

4.36E-01

TYPED

intronic

SUSD5

3p22.3

rs6110518

20

15,085,205

G

T

0.08761

1.92E-08

5.04E-01

IMPUTED

ICGC

intronic

MACROD2

20p12.1

rs908237

17

78,914,751

G

A

0.10847

3.01E-08

5.42E-01

IMPUTED

intronic

RPTOR

17q25.3

rs6597341

6

914,841

C

T

0.09013

5.83E-08

5.34E-01

IMPUTED

intergenic

LOC101927691;LINC01622

6p25.3

rs200334091

13

108,890,247

C

T

0.0891

1.79E-07

5.54E-01

IMPUTED

intergenic

ABHD13;TNFSF13B

13q33.3

rs76221875

4

86,702,592

G

A

0.09587

1.81E-07

5.53E-01

IMPUTED

ICGC

intronic

ARHGAP24

4q21.23

rs73149350

7

80,828,288

G

A

0.0721

2.19E-07

5.01E-01

IMPUTED

intergenic

SEMA3C;LOC105369146

7q21.11

rs11868975

17

2,664,626

A

G

0.09587

2.85E-07

5.49E-01

IMPUTED

intergenic

CCDC92B;RAP1GAP2

17p13.3

rs4635969

5

1,308,552

G

A

0.09294

2.98E-07

5.52E-01

TYPED

GWAS

downstream

MIR4457

5p15.33

rs72661905

13

113,568,986

C

T

0.07805

3.46E-07

5.28E-01

TYPED

ICGC

intergenic

ATP11A;MCF2L-AS1

13q34

rs117352285

11

42,410,962

C

T

0.08522

3.94E-07

5.34E-01

IMPUTED

intergenic

LINC02740;HNRNPKP3

11p12

rs11041484

11

7,641,520

G

A

0.08508

4.12E-07

5.45E-01

TYPED

GWAS

intronic

PPFIBP2

11p15.4

rs75488411

19

41,012,097

C

T

0.09048

4.17E-07

5.46E-01

TYPED

ICGC

COSMIC

intronic

SPTBN4

19q13.2

rs11829786

12

57,332,232

C

T

0.07762

4.43E-07

5.28E-01

IMPUTED

GWAS

intergenic

SDR9C7;RDH16

12q13.3

rs57845130

9

17,854,783

G

T

0.07597

5.99E-07

5.23E-01

TYPED

intergenic

SH3GL2;ADAMTSL1

9p22.2

rs35005811

3

14,376,664

T

G

0.24072

6.14E-07

1.41E + 00

IMPUTED

ICGC

intergenic

LSM3;LINC01267

3p25.1

rs78544457

5

121,659,085

G

T

0.10057

7.96E-07

5.84E-01

TYPED

intronic

SNCAIP

5q23.2

rs73584329

9

127,047,016

C

T

0.09449

8.12E-07

5.68E-01

TYPED

ICGC

intronic

NEK6

9q33.3

rs56354798

2

6,594,126

T

A

0.08099

8.53E-07

5.49E-01

IMPUTED

intergenic

LINC01247;LINC01246

2p25.2

rs116907254

14

21,313,268

C

T

0.09977

8.88E-07

5.77E-01

TYPED

ICGC

intergenic

RNASE1;RNASE3

14q11.2

rs12050132

14

73,276,250

A

T

0.50742

9.27E-07

1.34E + 00

IMPUTED

ICGC

GWAS

intronic

DPF3

14q24.2

rs75995217

7

88,849,880

C

G

0.07559

9.60E-07

5.41E-01

IMPUTED

intronic

ZNF804B

7q21.13

rs79192363

5

180,458,802

G

A

0.07741

9.88E-07

5.29E-01

IMPUTED

ICGC

intergenic

BTNL3;BTNL9

5q35.3

rs12813302

12

103,856,908

G

A

0.09099

1.28E-06

5.64E-01

TYPED

intronic

C12orf42

12q23.3

rs13381896

18

25,356,190

T

G

0.90662

1.97E-06

6.31E-01

TYPED

intergenic

LOC105372038;CDH2

18q12.1

rs74588014

9

138,726,580

C

A

0.0938

2.64E-06

5.85E-01

TYPED

intronic

CAMSAP1

9q34.3

rs434919

21

43,333,005

G

T

0.07181

3.14E-06

5.33E-01

IMPUTED

ICGC

GWAS

intronic

C2CD2

21q22.3

rs7973376

12

66,918,796

T

G

0.28683

3.50E-06

7.32E-01

IMPUTED

ICGC

intronic

GRIP1

12q14.3

rs4897331

6

129,866,547

C

T

0.08752

3.71E-06

5.80E-01

TYPED

ICGC

intergenic

LAMA2;ARHGAP18

6q22.33

rs2242402

17

77,918,261

G

A

0.09121

4.25E-06

5.93E-01

TYPED

intronic

TBC1D16

17q25.3

rs17719136

5

147,578,177

G

C

0.08744

4.39E-06

5.88E-01

TYPED

intergenic

SPINK14;SPINK6

5q32