Table 2 List of PharmVar annotated pharmacogenes, number of diplotypes and *alleles included in database
Pharmacogene | N Unique Diplotypes | N Unique *Alleles | N alleles annotated in PharmVar | Proportion Pharmvar annotated alleles in database |
|---|---|---|---|---|
CYP2A13 | 10 | 5 | 10 | 0.50 |
CYP2A6 | 34 | 13 | 43 | 0.30 |
CYP2B6 | 30 | 12 | 35 | 0.34 |
CYP2C19 | 44 | 14 | 75 | 0.19 |
CYP2C8 | 22 | 11 | 18 | 0.61 |
CYP2C9 | 33 | 15 | 85 | 0.18 |
CYP2D6 | 293 | 51a | 158a | 0.32 |
CYP3A4 | 31 | 18 | 35 | 0.51 |
CYP3A5 | 10 | 4 | 6 | 0.67 |
CYP4F2 | 6 | 3 | 3 | 1.00 |
DPYD | 61 | 24 | 408 | 0.06 |
NUDT15 | 5 | 4 | 20 | 0.20 |
SLCO1B1 | 84 | 22 | 42 | 0.52 |