Fig. 4

dN/dS mobilome analyses among the different M. ulcerans lineages and genomic elements present in M. ulcerans genomes. (a) Each point represents the average dN/dS value of an isolate and is grouped based on lineage. Mann-Whitney’s test was performed between lineage 1 and 2 and **** represents a p-value < 0.0001. (b) Each point represents the average dN/dS value of an isolate and is grouped based on lineage and the type of genomic element. Mann-Whitney’s test was performed between lineage 1 and 2 for each genomic element, and **** represents a p-value < 0.0001. (c) Distribution of mobilome-related genes and insertion sequence in African M ulcerans strains. The bar represents the distribution of the percentage of mobilome related-related genes in the functional genome. Only a single value is reported for the reference strain Agy99