Fig. 5

Cross-platform reproducibility of EPICv2. Principal component analysis (PCA) of the matched data (586,916 CpG sites) used in the cross-platform analysis, across a) EPICv1, b) EPICv2 and c) WGBS. Distributions of d) sensitivity to methylation change and e) precision of methylation measurement for the 586,916 CpG site summaries obtained via the row-linear method. f) Sensitivity and g) precision of EPICv1 and EPICv2 probes, split by Infinium probe type