Fig. 2

Schistosoma mansoni’s subtelomeres contribute to interchromosomal segmental duplications. A) Chromosomal map of segmental duplications (SD) highlighting regions of shared sequence similarity between S. mansoni chromosomes. SDs were classified as subtelomeric (if at least one of the two loci is subtelomeric, orange) or chromosome body (blue). The circle represents seven autosomal chromosomes (1–7) and two pseudoautosomal regions (PAR1 and PAR2). Chromosome bodies are shown in light grey, while subtelomeres are in dark grey. B) Differences in SD coverage for chromosome body and subtelomere of each chromosome were assessed (chi-squared test; * p < 0.05). C) The number of SDs in these regions was evaluated, generating an observed (O) vs. expected (E) ratio normalised by region size for each given chromosomal region, per chromosome (chi-squared test; *** p < 0.001). D) Nucleotide distance (Jukes-Cantor substitution model) of segmental duplications coloured by location