Table 1 The variation of non-synonymous single nucleotide polymorphism (SNPs) of PRNP in the five Nigerian livestock species
SNP location | Changes in Amino acid | Species |
|---|---|---|
G9A | M3K | All species |
G10A | M3K | All species |
C11G | M3K | All species |
G12C | A4S | All species |
C16G | N5K | Horse |
C24T | C8G | goat, sheep |
G30T | M10I | All species |
G34C | V12L | Dog |
C50T | A16V | Goat, sheep |
A51G | T17M | Camel, sheep, and goat |
C287G | T96S/A | Dog, goat, and sheep |
A296G | S98G | 21 goat individuals |
G340C | M113V | 2 sheep individuals |
T432C | S144N | Camel |
C480G | N160E | 3 dog individuals |
G501A | M167V | Horse |
G502A | M167V | Horse |
G503A | M167V | Horse |
G505C | D168S | Dog, camel, goat and sheep |
A506G | D168S | 2 sheep individuals |
T508G | D168S | 8 sheep individuals |
C510T | Y170D | Goat and sheep |
C522A | N174K | 24 sheep individuals |
A524G | N174K | Camel |
C534T | H178R | Dog, goat and sheep |
T612C T612G | V204M/I | Horse and camel Dog |
G618A | M206I | Horse, camel, goat and sheep |
G660A | E220Q | 1 individual dog |
G662A | E220Q | Horse and dog |
G663A | R221Q | Horse, camel, goat and sheep |
T669C | S223Y | All species |
G670G | S223Y | Dog and camel |
A678C A678G | Y226F/S | Dog Camel, goat and sheep |
T679C | Y226F/S | Horse |
C681A | Y227Q | Horse |
G693A G693C | S231A | Dog, goat and sheep Camel |
T699C | M233A | Dog |
G700A | M233A | Dog, camel, goat and sheep |
T711C T711G | S237P | Horse, camel, goat and sheep Dog |
C738G | F246L | Dog |