Fig. 4

Identification of 6mA in H. pylori genome. A The motif significantly enriched with 6 mA. Information content at a motif position, where all nucleoside with equal probability, was 0 bits, while a position with exclusive occurrence of a single nucleotide had an information content of 2 bits. B Circos plot illustrating the genomic distribution of 6mA. Blue, green and yellow rings represented the regions with high, moderate and low 6mA levels, respectively. Red ring represented gene expression level. C Number of genes with different 6mA levels. The genes were divided into low-6mA-density, moderate-6mA-density and high-6mA-density genes according to their 6mA density. D Correlation between the number of 6mA sites and the gene length