Fig. 5

A Patterns of nucleotide diversity across genomes of five inbred lines of Biomphalaria sudanica, highlighting two polymorphic transmembrane gene clusters that are orthologous to those previously associated with Schistosoma mansoni resistance in B. glabrata (PTC1 [41] and PTC2 [42]). B Genome-wide nucleotide diversity across overlapping 100-kb genomic windows (starting at 0-kb and 50-kb intervals) with windows on contigs 359 (PTC1) and 208 (PTC2) that occur in the top 1% of genome-wide nucleotide diversity between inbred lines being colored blue and red, respectively. C Genome-wide nucleotide diversity (purple line) and pairwise divergence for each haplotype pair (grey lines) across contigs 359 (PTC1) and 208 (PTC2). PTC1 and PTC2 regions are indicated by the blue and red bars, respectively. Similarly diverse regions span across several megabases of contig 208 in B. sudanica. Even in diverse regions, pairwise divergence can be near zero, indicating shared haplotypes