Table 1 Causal effects of 11 cis-pQTLs on telomere length
From: Insight into telomere regulation: road to discovery and intervention in plasma drug-protein targets
Tissue | Protein | UniProt ID | SNP | Effect allele | OR (95% CI) | P value | PVE | F statistics | Author |
|---|---|---|---|---|---|---|---|---|---|
Plasma | KDELC2 | A0A024R3C4;Q7Z4H8 | rs74911261 | A | 1.07 (1.06, 1.08) | 1.48E-44 | 8.61% | 310.89 | Sun |
Plasma | APOA5 | A0A0B4RUS7;Q6Q788 | rs964184 | C | 0.95 (0.93, 0.97) | 7.66E-06 | 1.56% | 52.29 | Sun |
Plasma | SERPINF1 | A0A140VKF3;P36955 | rs62088172 | T | 0.97 (0.96, 0.98) | 4.83E-10 | 8.69% | 314.18 | Sun |
Plasma | RPN1 | P04843 | rs2712417 | G | 0.96 (0.95, 0.97) | 3.81E-12 | 5.57% | 194.76 | Sun |
Plasma | LCT | P09848 | rs4988235 | A | 0.99 (0.98, 0.99) | 1.61E-05 | 23.45% | 1011.19 | Sun |
Plasma | TYMP | P19971 | rs131798 | G | 0.89 (0.87, 0.91) | 9.30E-24 | 1.42% | 46.24 | Emilsson |
Plasma | PSMB1 | P20618 | rs756519 | G | 0.98 (0.97, 0.98) | 5.19E-07 | 9.11% | 320.88 | Emilsson |
Plasma | GDI2 | P50395 | rs2890364 | G | 0.94 (0.92, 0.96) | 4.19E-08 | 1.75% | 57.03 | Emilsson |
Plasma | GSTO1 | P78417;V9HWG9 | rs2282326 | C | 0.99 (0.99, 0.99) | 2.12E-05 | 37.65% | 1993.36 | Sun |
Plasma | TYRO3 | Q06418 | rs2289743 | C | 1.11 (1.09, 1.15) | 2.88E-15 | 1.10% | 35.56 | Emilsson |
Plasma | NT5C | Q8TCD5;V9HWF3 | rs78625720 | A | 0.97 (0.95, 0.98) | 4.39E-05 | 3.21% | 109.65 | Sun |