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Fig. 6 | BMC Genomics

Fig. 6

From: JMJD3 regulate H3K27me3 modification via interacting directly with TET1 to affect spermatogonia self-renewal and proliferation

Fig. 6

In vivo functional validation of JMJD3. (A) Spermatogenesis disorder model mice transplantation of control PCDH and JMJD3 Positive Cells. (B) Chart of comparison of control PCDH with testes transplanted with JMJD3 positive cells. (C) HE staining plot of JMJD3 overexpression versus control PCDH. (D) Expression of JMJD3 in testicular spermatogonia after overexpression of JMJD3. (E) Expression of H3K27me3 and PCNA in testicular spermatogonia after JMJD3 overexpression. (F) Statistical analysis of JMJD3 + cells/H3K27m3 + cells and PCNA + cells in immunohistochemistry. Scale bar = 50 μm. n = 3

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BMC Genomics

ISSN: 1471-2164

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