Table 4 Correlation between genotypic and phenotypic resistance profiles of sequenced K. pneumoniae isolates
Strain | β Lactams | Carbapenem | Aminoglycosides | Fluoroquinolones | Miscellaneous | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Genotype | Phenotype | Genotype | Phenotype | Genotype | Phenotype | Genotype | Phenotype | Genotype | Phenotype | |
kp5 | SHV-11, CTX-M-15, TEM-1, | Resistant | NDM-4, OXA-10 | Resistant | armA, aph(6)-Id, aph(3″)-Ib | Resistant to all except CN | QnrB1, oqxA | Resistant to all except LEV | sul1, sul2, dfrA12, tetA | Resistant |
kp6 | SHV-11, TEM-1, | Resistant | NDM-4, OXA-10 | Resistant | armA | Resistant | oqxA | Resistant | sul1, sul2, | Resistant |
kp10 | SHV-28,, TEM-1, CTX-M-15, | Resistant | OXA-1, CMY-4 | Resistant to MEM Susceptible to IMP | aph(3″)-Ib, aph(6)-Id, aac(6′)-Ib-cr | Intermediate Susceptible | QnrS1, aac(6′)-Ib-cr, oqxA | Resistant | sul-2, dfrA14, tetA | Resistant |
kp47 | SHV-32 | Resistant | Nil | Resistant | Nil | Resistant | QnrB1 | Resistant | KpnF | Resistant |
kp54 | SHV-187, CTX-M-15, TEM 1, | Resistant | NDM 1 | Resistant | aac(3)-Iid, aadA2, rmtB | Resistant | aac(6′)-Ib-cr | Resistant | sul 1, drfA12, dfrA27 | Resistant |
kp58 | SHV-1 | Resistant | Nil | Resistant | Nil | Susceptible to AK, CN Resistant to TOB | oqxA | Resistant | Nil | Resistant |
kp106 | SHV-1, TEM-1, CTX-M-15 | Resistant | OXA-232, NDM-5, | Resistant | rmtB, aadA2 | Resistant | QnrS1 | Resistant | sul1, dfrA12 | Resistant |
kp126 | SHV-1, CTX-M-15,TEM-1, | Resistant | NDM-5 | Resistant | Nil | Susceptible to AK, CN Intermediate to TOB | QnrB6 | Intermediate | dfrA12, sul 1, sul 2 | Resistant |
kp127 | SHV-1, CTX-M-15, TEM-1, | Resistant | NDM-5 | Resistant | aac(6′)-Ib-cr, aph(3″)-Ib, aph(6)-Id | Susceptible | QnrB6, aac(6′)-Ib-cr | Intermediate | sul-1, sul-2 | Resistant |
kp128 | SHV-1, CTX-M-15,,TEM-1, | Resistant | NDM-5 | Resistant | aac(6′)-Ib-cr, aph(3″)-Ib, aph(6)-Id | Resistant | QnrB6, aac(6′)-Ib-cr | Resistant | sul-1, sul-2 | Resistant |