Table 5 Functional & structural consequences of SNPs
Protein | Mutation | SIFT | MUpro | |||
|---|---|---|---|---|---|---|
Score | Prediction | â–²G | Confidence Score | Prediction | ||
Ompk36 | Val178Pro | 0.62 | Tolerated | −1.295 | −1 | Decreases Stability |
Thr258Ser | 0.04 | Affect Protein Function | −1.048 | 0.97 | Decreases Stability | |
Leu307Ile | 0.55 | Tolerated | −0.389 | −1 | Decreases Stability | |
Ile315Leu | 1.00 | Tolerated | −0.488 | −1 | Decreases Stability | |
Asp344Glu | 0.43 | Tolerated | −0.809 | −0.5 | Decreases Stability | |
His349Arg | 0.56 | Tolerated | −0.879 | 0.82 | Decreases Stability | |