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Fig. 2 | BMC Genomics

Fig. 2

From: Identification and validation of RNA-binding protein SLC3A2 regulates melanocyte ferroptosis in vitiligo by integrated analysis of single-cell and bulk RNA-sequencing

Fig. 2

ScRNA-seq analysis of skin from healthy donors and patients with vitiligo identified distinct cell types. (A, B) UMAP plot of composite single-cell transcriptomic profiles from all 15 skin samples from healthy donors and patients with vitiligo. Colors indicate cell clusters along with annotations. Mono. Phagocyte: mononuclear phagocyte. (C) UMAP plot split by different sample groups. (D) Bar plot comparing the proportions of cell populations of each cell type within each sample group. (E) Rank order based on decreasing values of the relative frequency ratio between two sample groups. (F) Difference in the proportion of cell clusters between two sample groups

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