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Fig. 4 | BMC Genomics

Fig. 4

From: Identification and validation of RNA-binding protein SLC3A2 regulates melanocyte ferroptosis in vitiligo by integrated analysis of single-cell and bulk RNA-sequencing

Fig. 4

Functional RBPs are differentially regulated in melanocytes of patients with vitiligo and healthy donors. (A) Dot plot showing several differentially expressed RBPs in each cell type between vitiligo and healthy sample groups. (B) Scatter plot displaying differentially expressed RBPs in C2 melanocytes. Red color indicates significantly altered RBPs. (C) Gene expression levels of S100A4 in different sample groups represented in UMAP plot. (D) Violin plot of BST2 in each cell type in different sample groups. (E) Cytoscape shows co-expression networks comprising SLC3A2 from C2 melanocyte cell clusters. Edges connect RBP-target gene pairs, while nodes represent genes. RBPs are displayed in larger font and red color. (F) Enriched biological processes of target genes for SLC3A2 from E are shown

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BMC Genomics

ISSN: 1471-2164

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