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Fig. 4 | BMC Genomics

Fig. 4

From: Integrated Metabolomic and transcriptomic analyses reveal deoxycholic acid promotes transmissible gastroenteritis virus infection by inhibiting phosphorylation of NF-κB and STAT3

Fig. 4

Effects of DCA addition on PEDV replication in ST cells. (a) Viability of ST cells treated for 48 h with DCA at various doses (12.5 µM, 25 µM, 50µM). (b) Relative expression of TGEV N gene after 48 h of TGEV infection. The results are represented as the mean ± SD of three separate tests (n = 3). **P<0.01. (c) Western blot of TGEV-N protein. (d) The titer of TGEV treated with DCA after 48 h. (e) Relative expression of antiviral genes. (f) Western blot of p-p65 and p-STAT3 protein. MOCK: ST cells; TGEV: ST cells infected with TGEV; TGEV + 12.5 µM DCA: ST cells infected with TGEV and treated with DCA.

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BMC Genomics

ISSN: 1471-2164

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