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Table 2 Lead SNPs across cohorts. List of the general CHD lead SNP across the cohorts used in this study. NA signifies not available (SNP not present in summary statistics). OR [95% CI] signifies Odds ratio [95% confidence interval]

From: Genome-wide association studies highlight novel risk loci for septal defects and left-sided congenital heart defects

 

FinnGen

 

UKB

 

Meta-analysis

 

SNP

OR [95% CI]

p

OR[95%CI]

p

OR[95%CI]

p

rs35046143

1.15[1.10–1.21]

7.1 × 10–9

NA

NA

NA

NA

rs2316327

1.17[1.12–1.23]

1.5 × 10–9

1.08[1.00–1.17]

6.0 × 10–2

1.14[1.09–1.20]

2.0 × 10–9

rs1293973611

4.48[2.80–7.17]

7.0 × 10–10

NA

NA

NA

NA

rs16941382

1.17[1.11–1.24]

5.5 × 10–9

1.11[1.02–1.19]

2.1 × 10–2

1.15[1.11–1.20]

1.5 × 10–9