Fig. 5

Crosstalk between myeloid cells or T cells and other cells in BRCA. A, B Circle plots show the up- or downregulated pathway of myeloid cells (A) or T cells (B) as source cells in communication with other cells in the tumor group compared with those in the normal group. C Bubble plots display the main signaling pathways mediating the cellular interaction from myeloid cells (left) or T cells (right) to other cells. D, E Violin plots show the detailed expression of the genes related to the MIF pathway (D) and the MHC II pathway (E) in each cell type in the different groups. F Venn plot of the intersection genes of FLI1 target genes and ligand-receptor genes in cellular communication. G Bubble plots presenting the KEGG analysis results of the intersection genes of FLI1 target genes and ligand-receptor genes. H A graph shows the potential mechanism by which FLI1 regulates immune cell interactions in BRCA