Table 7 Top 5 GO terms enriched in genes associated with super-enhancers in differentiating bovine satellite cells
GO category | GO term | Count of genes | Fold enrichment | P-value | FDR |
|---|---|---|---|---|---|
Biological process | negative regulation of angiogenesis (GO:0016525) | 5 | 11.1 | 0.000 | 0.013 |
actin filament depolymerization (GO:0030042) | 4 | 11.1 | 0.001 | 0.034 | |
muscle cell development (GO:0055001) | 14 | 8.6 | 0.000 | 0.000 | |
activin receptor signaling pathway (GO:0032924) | 5 | 8.5 | 0.001 | 0.025 | |
striated muscle cell development (GO:0055002) | 9 | 8.3 | 0.000 | 0.001 | |
Cellular component | Z disc (GO:0030018) | 14 | 8.6 | 0.000 | 0.000 |
I band (GO:0031674) | 14 | 8.4 | 0.000 | 0.000 | |
focal adhesion (GO:0005925) | 21 | 7.9 | 0.000 | 0.000 | |
cell-substrate junction (GO:0030055) | 22 | 7.7 | 0.000 | 0.000 | |
sarcomere (GO:0030017) | 19 | 7.5 | 0.000 | 0.000 | |
Molecular function | collagen binding (GO:0005518) | 5 | 7.4 | 0.001 | 0.028 |
cadherin binding (GO:0045296) | 14 | 4.9 | 0.000 | 0.000 | |
actin binding (GO:0003779) | 50 | 4.4 | 0.000 | 0.000 | |
transmembrane receptor protein kinase activity (GO:0019199) | 14 | 4.4 | 0.000 | 0.001 | |
phosphatidylinositol bisphosphate binding (GO:1,902,936) | 8 | 4.3 | 0.001 | 0.024 |