Table 3 The top 10 most significantly overexpressed genes in each cluster, compared to the other clusters
From: Intestinal cell diversity and treatment responses in a parasitic nematode at single cell resolution
Cluster | Gene ID | Functional annotation | Phylogenetic Conservation | Log2 Fold Change | Adjusted P value |
|---|---|---|---|---|---|
Cluster 1 | AgR002_g271 | otud4: Zgc:165,536 protein | Nematode-specific | 1.66 | 0 |
AgR049_g076 | - | Ascaris-specific | 0.52 | 0 | |
AgR049_g078 | - | Ascaris-specific | 0.50 | 0 | |
AgR001_g371 | GRANULINS domain-containing protein | Ascaris-specific | 0.49 | 0 | |
AgB23_g001 | - | A. suum-specific | 0.47 | 0 | |
AgR028_g116 | fabG: DeHydrogenases, Short chain | Nematodes & hosts | 0.43 | 0 | |
AgB04_g312 | eef2: Elongation factor 2 | Nematodes & hosts | 0.43 | 0 | |
AgR207X_g001 | clec-160: C-type lectin protein | Nematode-specific | 0.43 | 0 | |
AgR063_g005 | vit-6: Vitellogenin-6 | Nematodes & hosts | 0.41 | 0 | |
AgR159_g003 | vit-6: Vitellogenin-6 | Nematodes & hosts | 0.41 | 0 | |
Cluster 2 | AgB01_g233 | - | A. suum-specific | 2.95 | 0 |
AgB01_g238 | - | A. suum-specific | 2.84 | 0 | |
AgR007_g007 | - | Ascaris-specific | 2.69 | 0 | |
AgB04_g065 | IPR001005: SANT/Myb domain | Ascaris-specific | 2.54 | 0 | |
AgR006_g005 | tos-1 (Target Of Splicing) | Nematode-specific | 2.42 | 0 | |
AgR009X_g305 | Transmembrane protein | Ascaris-specific | 2.28 | 0 | |
AgR039_g009 | Endoribonuclease XendoU | Nematodes & hosts | 2.16 | 0 | |
AgR019X_g186 | - | Clade III-specific | 2.13 | 0 | |
AgB13X_g054 | Nuclear factor related to kappa-B-binding | Nematode-specific | 2.11 | 0 | |
AgB01_g234 | - | A. suum-specific | 2.06 | 0 | |
Cluster 3 | AgR013X_g192 | vit-6: Vitellogenin-6 | Nematodes & hosts | 1.19 | 0 |
AgB02_g451 | ABA-1: Polyprotein ABA-1 | Nematode-specific | 1.15 | 0 | |
AgR011_g069 | GOLGB1: golgin subfamily B member 1 | Nematode-specific | 1.11 | 0 | |
AgR005_g235 | vit-6: Vitellogenin-6 | Nematodes & hosts | 1.08 | 0 | |
AgR011_g070 | GOLGB1: golgin subfamily B member 1 | Ascaris-specific | 1.07 | 0 | |
AgR015_g155 | ASU_02895: Apolipophorin | Nematodes & hosts | 1.06 | 0 | |
AgR063_g005 | vit-6: Vitellogenin-6 | Nematodes & hosts | 1.04 | 0 | |
AgR159_g003 | vit-6: Vitellogenin-6 | Nematodes & hosts | 1.00 | 0 | |
AgR001_g371 | GRANULINS domain-containing protein | Ascaris-specific | 0.90 | 0 | |
AgR028_g116 | fabG: DeHydrogenases, Short chain | Nematodes & hosts | 0.89 | 0 |