Fig. 3

iRIP-seq of HMGB1 bound-RNAs in HeLa cells. A Table summarizing the number of total mapped reads to the human genome for the iRIP-seq duplicates. B Genomic distribution of HMGB1-bound peaks called by ABLIRC algorithm. C The top 10 representative GO biological process terms of HMGB1-regulated genes overlap with HMGB1-bound genes. X-axis represents the base 10 logarithm of the enrichment p-value, y-axis represents the term of enriched GO pathways. D Venn diagram showing the overlapped genes between DEGs by HMGB1-OE and HMGB1-bound genes. E Extracted HMGB1 peaks motifs using ABLIRC or Piranha. F Percentage of iRIP-seq reads that blast to the Rfam database: long intergenic ncRNA (linRNA), microRNA (miRNA), ribosomal RNA (rRNA), 5S ribosomal RNA (5S rRNA), 5.8S ribosomal RNA (5.8S rRNA), small nuclear RNA (snRNA), transfer RNA (tRNA) or other ncRNA relative to the total number of ncRNA. Red and dark blue column represent IP1 and IP2, respectively